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$445.00
| Cat.#: 28471 | ||
| Product Name: Anti-IL17RA(DM126) Rabbit Monoclonal Antibody | ||
| Synonyms: CD217;CDw217;IL-17RA;IL17R;CANDF5;hIL-17R | ||
| Description: Anti-IL17RA antibody(DM126) Rabbit Monoclonal Antibody | ||
| Background: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. | ||
| Applications: ELISA; Flow Cyt | ||
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||
| Host Species: Rabbit | ||
| Isotype: Rabbit IgG | ||
| Purification: Purified from cell culture supernatant by affinity chromatography | ||
| Species Reactivity: Human IL17RA | ||
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||
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