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Mouse FAP Protein, N-mFc Tag

Recombinant mouse FAP protein with N-mFc tag


Cat.#:  11328

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11328
Product Name:   Mouse FAP Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   SIMP;APCE
Target:    FAP
UNIPROT ID:    P97321
Description:    Recombinant mouse FAP protein with N-mFc tag
Background:     This gene belongs to the serine protease family. The encoded protein is an inducible cell-surface bound glycoprotein specifically expressed in tumor-associated fibroblasts and pericytes of epithelial tumors and has protease and gelatinase activity. The protein plays a role in remodeling of the extracellular matrix (ECM) and may affect tumorigenesis and tissue repair. Alternately spliced transcript variants of this gene are described in the literature (PMID 9139873), but the full-length sequence of these variants is not available.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 111.5 kDa after removal of the signal peptide.The apparent molecular mass of mFc-Mouse-FAP is approximately 130 kDa due to glycosylation.
Molecular Characterization:    mFc(Pro99-Lys330) Mouse FAP(Leu26-Asp761)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse FAP Protein, N-mFc Tag on SDS-PAGE under reducing condition.