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Mouse TNFRSF10B Protein, hFc Tag

Recombinant mouse TNFRSF10B protein with C-terminal human Fc tag
5/5

$550.00

Cat.#:  12181

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     12181
Product Name:   Mouse TNFRSF10B Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Death receptor 5;MK;CD262
Target:    TNFRSF10B
UNIPROT ID:    Q9QZM4
Description:    Recombinant mouse TNFRSF10B protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 40.3 kDa after removal of the signal peptide. The apparent molecular mass of mTNFRSF10B-hFc is approximately 40-55 kDa due to glycosylation.
Molecular Characterization:    Mouse TNFRSF10B(Asn53-Lys180) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse TNFRSF10B Protein, hFc Tag on SDS-PAGE under reducing condition.
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