| Cat.#: 11112 |
| Product Name: Human NTSR1 Full Length Protein |
| Size : 10 µg; 50 µg and 100 µg |
| Synonyms: NTR |
| Target: NTSR1 |
| UNIPROT ID: P30989 |
| Description: Human NTSR1 Full Length Protein-Synthetic Nanodisc |
| Background: Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. |
| Species/Host: HEK293 |
| Molecular Weight: The human full length NTSR1 protein has a MW of 46.1 kDa |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Protein Families: Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Figure 1. Elisa plates were pre-coated with Flag Tag NTSR1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with NTSR1-Nanodisc is 2.583ng/ml. | 
Figure 2. Human NTSR1-Nanodisc, Flag Tag on SDS-PAGE |
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