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Human P2RX7 Full Length Protein

Human P2RX7 Full Length Protein-Synthetic Nanodisc


Cat.#:  11030

   Size:   50 μg

3-4 weeks

          Product Description          
Cat.#:     11030
Product Name:   Human P2RX7 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   P2X7
Target:    P2RX7
UNIPROT ID:    Q99572
Description:    Human P2RX7 full length protein-synthetic nanodisc
Background:     The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
Species/Host:    HEK293
Molecular Weight:    The human full length P2RX7 protein has a MW of 68.4 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag P2RX7-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with P2RX7-Nanodisc is 5.349ng/ml.

Figure2. Human P2RX7-Nanodisc, Flag Tag on SDS-PAGE