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PIK3CA(Q546K)

Anti-PIK3CA(Q546K) Mouse Monoclonal Antibody
5/5

$495.00

Cat.#:  26138

   Size:   100 μl

In Stock

          Product Description          
PIK3CA(Q546K)
Cat. #:   26138
Size:  100 µL
Gene Symbol:  PIK3CA
Description:   Anti-PIK3CA(Q546K) Mouse Monoclonal Antibody
Background:   Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform. Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Belongs to the PI3/PI4-kinase family. Located to cytosol, lamellipodium and phosphatidylinositol 3-kinase complex.
Immunogen:   A synthetic peptide from the internal region of PIK3CA(Q546K) of human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:    ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:100
Concentration:   0.2 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   
Purity:   Purified from ascites
Preservative:  No
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  recognizes Q546K mutant, but not wild type PIK3CA of vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing
Western blot:   Western blot analysis of PIK3CA wild type and Q546K proteins. Equal amount of purified PIK3CA(Q546K)(amino acids 461-640) and corresponding wild type proteins were loaded and blotted with anti-PIK3CA(Q546K) mouse monoclonal antibody(Cat. # 26138).
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