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Human PLA2R1 Full Length Protein

Human PLA2R1 Full Length Protein-Synthetic Nanodisc


Cat.#:  11128

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11128
Product Name:   Human PLA2R1 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
Target:    PLA2R1
UNIPROT ID:    Q13018
Description:    Human PLA2R1 full length protein-synthetic nanodisc
Background:     This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Species/Host:    HEK293
Molecular Weight:    The human full length PLA2R1 protein has a MW of 168.6 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag PLA2R1-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with PLA2R1-Nanodisc is 3.595ng/ml.

Figure2. Human PLA2R1-Nanodisc, Flag Tag on SDS-PAGE