$239.00
| Cat. #: 26007 |
| Gene Symbol: RHOA |
| Description: Anti-RhoA Mouse Monoclonal Antibody |
| Background: Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca2+ sensitivity of smooth muscle contraction. |
| Immunogen: : Recombinant full length protein of RhoA. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:1000-1:2000 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: : PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: RhoA antibody recognizes RhoA from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of RhoA proteins. MEF whole-cell lysate was used for western blot with the anti-RhoA mouse monoclonal antibody (cat. # 26008). | 1. Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds Commun Biol. 2021 PMID: 34145387 |
| 2. Acute compressive stress activates RHO/ROCK-mediated cellular processes Small GTPases 2020 PMID: 29455593 |
| 3. Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells FASEB J. 2018 PMID: 29447006 |
| 4. Social Isolation Induces Rac1-Dependent Forgetting of Social Memory Cell Rep. 2018 PMID: 30304669 |
| 5. The Heterotaxy Gene CCDC11 is Essential for Cytokinesis and Cell-Cell Adhesion via RhoA Regulation bioRxiv. 2018 PMID: |
| 6. Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers Gastroenterology. 2017 PMID: 28522256 |
