Email: info@neweastbio.com   |  Call: 6109452007

RhoA pAb

  Anti RhoA Rabbit Polyclonal Antibody
5/5

$219.00

Cat.#:  21017

   Size:   100 μl

In Stock

          Product Description          

RhoA Polyclonal Antibody

Cat. #:  21017
Gene Symbol:  RHOA
Description:   Anti-RhoA Rabbit Polyclonal Antibody
Background:   Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca2+ sensitivity of smooth muscle contraction.
Immunogen:   A synthetic peptide from the C-terminal region of RhoA.
Applications:   ELISA, WB, IHC, IP
Recommended Dilutions:   
ELISA: 1:100-1:5000
WB: 1:100-1:2000
IHC: 1:10-1:1000
Concentration:    0.2 mg/ml
Host Species:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Purity:   Purified from serum
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 51% glycerol Species
Species Reactivity:  RhoA antibody recognizes RhoA from vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing

Western blot:  

Western blot analysis of RhoA proteins.

Purified recombinant His-RhoA protein was used for western blot with the anti RhoA rabbit polyclonal antibody (Cat. # 21017).

          Publications          


01. Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity
Neuron. 2022  PMID: 36323321
02. Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds
Commun Biol. 2021  PMID: 34145387
03. Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior
Mol Psychiatry. 2020  PMID: 30120419
04. Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis
Sci Rep. 2019  PMID: 31406143
05. Inhibition of Notch1 signaling promotes neuronal differentiation and improves functional recovery in spinal cord injury through suppressing the activation of Ras homolog family member A
J Neurochem. 2019  PMID: 31339573
06. Simulated microgravity inhibits the viability and migration of glioma via FAK/RhoA/Rock and FAK/Nek2 signaling
In Vitro Cell Dev Biol Anim., 2019  PMID: 30820814
07. Potential Regulatory Effects of Corticotropin-Releasing Factor on Tight Junction-Related Intestinal Epithelial Permeability are Partially Mediated by CK8 Upregulation
Cell Physiol Biochem. 2017  PMID: 29179184
08. Converging, Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses
J Neurosci. 2016  PMID: 27807170
09. Elongator controls cortical interneuron migration by regulating actomyosin dynamics
Cell Res. 2016  PMID: 27670698
10. Simvastatin prevents and reverses chronic pulmonary hypertension in newborn rats via pleiotropic inhibition of RhoA signaling
Am J Physiol Lung Cell Mol Physiol. 2016  PMID: 27694473
11. Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence
EMBO Mol Med. 2013  PMID: 23853104
12. Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway
J Neurochem. 2013  PMID: 23895422