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CD40L mAb (Ruplizumab)

Anti-CD40L? Monoclonal Antibody (RuplizuMonoclonal Antibody)?


Cat.#:  28051

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28051
Product Name:   Anti-CD40L (Ruplizumab) Monoclonal Antibody
Synonyms:   CD40LG;D154;D40L;IGM1;GM;MD3;-BAM;NFSF5;RAP;p39
Description:    Anti-CD40L (ruplizumab ) Monoclonal Antibody
Background:    Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Humanized
Isotype:    IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD40 Ligand
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human CD40L, hFc tagged protein (11241) can bind Anti-CD40L Neutralizing antibody (28051) in a linear range of 0.64-400 ng/ml. In order to specifically detect 28051, mouse anti-human Fab-specific antibody was used as detection antibody.

Figure 2. HEK293 cell line transfected with irrelevant protein  (B) and human CD40L  (A) were surface stained with Anti-CD40L mAb 1 µg/ml  (ruplizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.