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Human TSHR Full Length Protein

Human TSHR Full Length Protein-Synthetic Nanodisc


Cat.#:  11026

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11026
Product Name:   Human TSHR Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CHNG1; hTSHR-I; LGR3
Target:    TSHR
UNIPROT ID:    P16473
Description:    Human TSHR full length protein-synthetic nanodisc
Background:     The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.
Species/Host:    HEK293
Molecular Weight:    The human full length TSHR protein has a MW of 86.8 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag TSHR-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TSHR-Nanodisc is 2.108ng/ml.

Figure2. Human TSHR-Nanodisc, Flag Tag on SDS-PAGE