| Cat.#: 11026 |
| Product Name: Human TSHR Full Length Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: CHNG1; hTSHR-I; LGR3 |
| Target: TSHR |
| UNIPROT ID: P16473 |
| Description: Human TSHR full length protein-synthetic nanodisc |
| Background: The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. |
| Species/Host: HEK293 |
| Molecular Weight: The human full length TSHR protein has a MW of 86.8 kDa |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure1. Elisa plates were pre-coated with Flag Tag TSHR-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TSHR-Nanodisc is 2.108ng/ml. | 
Figure2. Human TSHR-Nanodisc, Flag Tag on SDS-PAGE |
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