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VEGFR2 (DM185) Rabbit mAb

Anti-VEGFR2 (DM185) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28528

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28528
Product Name:   Anti-VEGFR2(DM185) Rabbit Monoclonal Antibody
Synonyms:   CD309; FLK1; VEGFR; VEGFR2
Description:    Anti-VEGFR2 antibody(DM185) Rabbit Monoclonal Antibody
Background:    Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor; known as kinase insert domain receptor; is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation; survival; migration; tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors; including Rab GTPase; P2Y purine nucleotide receptor; integrin alphaVbeta3; T-cell protein tyrosine phosphatase; etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human VEGFR2
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-VEGFR2 (DM185) on Expi293 cells transfected with human VEGFR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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