Email:   |  Call: 6109452007

YAP1 (DMC495) IgG1 Chimeric mAb

Anti-YAP1 (DMC495) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28268

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28268
Product Name:   Anti-YAP1(DMC495) IgG1 Chimeric Monoclonal Antibody
Synonyms:   COB1; YAP; YAP2; YAP65; YKI
Description:    Anti-YAP1 antibody(DMC495) IgG1 Chimeric Monoclonal Antibody
Background:    This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development; growth; repair; and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human YAP1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-YAP1 (DMC495) on Expi293 cells transfected with human YAP1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).