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Tuberin Rabbit mAb

Anti-Tuberin Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263590

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263590
Product Name:   Anti-Tuberin Rabbit Monoclonal Antibody
Synonyms:   TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4
UNIPROT ID:   P49815
Background:    Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity.
Immunogen:    Recombinant protein of human Tuberin
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-1I3
MW:    Calculated MW: 201 kDa; Observed MW: 201 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Tuberin in Hela, A549, HL-60, U2OS lysates using Tuberin antibody.
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