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ADGRE2 (DMC370) IgG1 Chimeric mAb

Anti-ADGRE2 (DMC370) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28203

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28203
Product Name:   Anti-ADGRE2(DMC370) IgG1 Chimeric Monoclonal Antibody
Synonyms:   Adhesion G protein-coupled receptor E2;EGF-like module receptor 2;EGF-like module-containing mucin-like hormone receptor-like 2;CD312
Description:    Anti-ADGRE2 antibody(DMC370) IgG1 Chimeric Monoclonal Antibody
Background:    This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human ADGRE2
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-ADGRE2 (DMC370) on Expi293 cells transfected with human ADGRE2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).