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ACIN1 Rabbit pAb

Anti-ACIN1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220260

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220260
Product Name:   Anti-ACIN1 Rabbit Polyclonal Antibody
Synonyms:   ACN; ACINUS; fSAP152
UNIPROT ID:   Q9UKV3 (Gene Accession – NP_001158286 )
Background:    Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen:    Synthetic peptide of human ACIN1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220260(ACIN1 Antibody) at a dilution of 1/80(Nucleus, Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220260(Anti-ACIN1 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 220260(Anti-ACIN1 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D261222(Anti-ACIN1 Antibody) at dilution 1/80.
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