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Human CAV1 Full Length Protein

Human CAV1 Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11123

   Size:   50 μg

In Stock

            Product Description          
Cat.#:     11123
Product Name:   Human CAV1 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Target:    CAV1
UNIPROT ID:    Q03135
Description:    Human CAV1 full length protein-synthetic nanodisc
Background:     The scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Species/Host:    HEK293
Molecular Weight:    The human full length CAV1 protein has a MW of 20.3 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CAV1-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CAV1-Nanodisc is 4.671ng/ml.

Figure2. Human CAV1-Nanodisc, Flag Tag on SDS-PAGE
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