| Cat.#: 11063 |
| Product Name: Human CLDN2 Full Length Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: OAZON |
| Target: CLDN2 |
| UNIPROT ID: P57739 |
| Description: Human CLDN2 full length protein-synthetic nanodisc |
| Background: This protein belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. |
| Species/Host: HEK293 |
| Molecular Weight: The human full length CLDN2 protein has a MW of 24.5 kDa |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure1. Elisa plates were pre-coated with Flag Tag CLDN2-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CLDN2-Nanodisc is 6.681ng/ml. | 
Figure2. Human CLDN2-Nanodisc, Flag Tag on SDS-PAGE |
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