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Human CLDN9 Full Length Protein

Human CLDN9 Full Length Protein-Synthetic Nanodisc


Cat.#:  11062

   Size:   50 μg

3-4 weeks

          Product Description          
Cat.#:     11062
Product Name:   Human CLDN9 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   DFNB116
Target:    CLDN9
UNIPROT ID:    O95484
Description:    Human CLDN9 full length protein-synthetic nanodisc
Background:     This protein is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.
Species/Host:    HEK293
Molecular Weight:    The human full length CLDN9 protein has a MW of 22.8 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CLDN9-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CLDN9-Nanodisc is 6.168ng/ml.

Figure2. Human CLDN9-Nanodisc, Flag Tag on SDS-PAGE