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GUCY2C (DMC387) IgG1 Chimeric mAb

Anti-GUCY2C (DMC387) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28205

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28205
Product Name:   Anti-GUCY2C(DMC387) IgG1 Chimeric Monoclonal Antibody
Description:    Anti-GUCY2C antibody(DMC387) IgG1 Chimeric Monoclonal Antibody
Background:    This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin; and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human GUCY2C
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-GUCY2C (DMC387) on Expi293 cells transfected with human GUCY2C (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).