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Human ANGPT2 Protein, hFc Tag

Recombinant human ANGPT2 protein with C-terminal human Fc tag


Cat.#:  11604

   Size:   100 μg

Under development

          Product Description          
Cat.#:     11604
Product Name:   Human ANGPT2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ANGPT2;GPT2;NG2;ngiopoietin-2
Target:    ANGPT2
UNIPROT ID:    O15123
Description:    Recombinant human ANGPT2 protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 49.94 kDa after removal of the signal peptide.
Molecular Characterization:    ANGPT2(Lys275-Phe496) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.