Subtotal:
$248.00
$525.00
| Cat.#: 11314 | ||
| Product Name: Human BCMA Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: TNFRSF17;CD269;BCM;BCMA | ||
| Target: BCMA | ||
| UNIPROT ID: Q02223 | ||
| Description: Recombinant Human BCMA Protein with C-terminal 6xHis tag | ||
| Background: B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 6.7kDa after removal of the signal peptide. | ||
| Molecular Characterization: BCMA(Met1-Ala54) 6×His tag | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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