Subtotal:
$239.00
$525.00
| Cat.#: 11293 | ||||
| Product Name: Human CD155 Protein | ||||
| Size : 10 µg, 50 µg and 100 µg | ||||
| Synonyms: PVR;FLJ25946;PVS;CD155;TAGE4;HVED;NECL5 | ||||
| Target: CD155 | ||||
| UNIPROT ID: P15151 | ||||
| Description: Recombinant human CD155 protein with C-terminal human Fc tag | ||||
| Background: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. | ||||
| Species/Host: HEK293 | ||||
| Molecular Weight: The protein has a predicted molecular mass of 61.2 kDa after removal of the signal peptide. The apparent molecular mass of CD155-hFc is approximately 70-100 kDa due to glycosylation. | ||||
| Molecular Characterization: CD155(Trp21-Asn343) hFc(Glu99-Ala330) | ||||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||||
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