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Human CDH17(567-667) Protein, hFc Tag

Recombinant human CDH17(567-667) Protein with C-terminal human Fc tag


Cat.#:  11243

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11243
Product Name:   Human CDH17(567-667) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CDH16;HPT-1;HPT1
Target:    CDH17
UNIPROT ID:    Q12864
Description:    Recombinant human CDH17(567-667) Protein with C-terminal human Fc tag
Background:     This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 37.0 kDa after removal of the signal peptide. The apparent molecular mass of CDH17(567-667)-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    CDH17(Ser567-Leu667) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CDH17(567-667) Protein, hFc Tag on SDS-PAGE under reducing condition.