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Human DAP10 Protein, hFc Tag

Recombinant human DAP10 protein with C-terminal human Fc tag
5/5

$389.00

Cat.#:  11500

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11500
Product Name:   Human DAP10 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   HCST;KAP10;PIK3AP
Target:    DAP10
UNIPROT ID:    Q9UBK5
Description:    Recombinant human DAP10 protein with C-terminal human Fc tag
Background:     This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 29.1 kDa after removal of the signal peptide. The apparent molecular mass of DAP10-hFc is approximately 25-55 kDa due to glycosylation.
Molecular Characterization:    DAP10(Gln19-Pro48) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human DAP10 Protein, hFc Tag on SDS-PAGE under reducing condition.
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