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Human IgG1-Fc Protein

Recombinant Human IgG1-Fc Protein


Cat.#:  11303

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11303
Product Name:   Human IgG1-Fc Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   IgG1 Fc Protein
Target:    IgG1-Fc
UNIPROT ID:    P01857
Description:    Recombinant Human IgG1-Fc Protein
Background:     IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)) is a Protein Coding gene. Diseases associated with IGHG1 include?Leukemia, Chronic Lymphocytic?and?Heavy Chain Deposition Disease. Among its related pathways are?Interleukin-4 and 13 signaling?and?IL4-mediated signaling events. Gene Ontology (GO) annotations related to this gene include?antigen binding. An important paralog of this gene is?IGHG3.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 27.7 kDa after removal of the signal peptide.The apparent molecular mass of IgG1-Fc is approximately 30-40 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IgG1-Fc Protein on SDS-PAGE under reducing condition.