Subtotal:
$495.00
$445.00
| Cat.#: 11759 | ||||
| Product Name: Human IL21 Protein | ||||
| Size : 10 µg, 50 µg and 100 µg | ||||
| Synonyms: IL21;a11;nterleukin-21 | ||||
| Target: IL21 | ||||
| UNIPROT ID: Q9HBE4 | ||||
| Description: Recombinant Human IL21 with C-terminal Human Fc tag | ||||
| Background: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] | ||||
| Species/Host: HEK293 | ||||
| Molecular Weight: The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide.The apparent molecular mass of IL21-hFc is approximately 35-55 kDa due to glycosylation. | ||||
| Molecular Characterization: IL21(Gln30-Ser162) hFc(Glu99-Ala330) | ||||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||||
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