Email:   |  Call: 6109452007

Human ITGB1 Protein, hFc Tag

Recombinant human ITGB1 protein with C-terminal human Fc tag


Cat.#:  11258

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11258
Product Name:   Human ITGB1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   GPIIA;CD29;VLA-4 subunit beta
Target:    ITGB1
UNIPROT ID:    P05556
Description:    Recombinant human ITGB1 protein with C-terminal human Fc tag
Background:     Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGB1-hFc is approximately 130-250 kDa due to glycosylation.
Molecular Characterization:    ITGB1(Gln21-Asp728) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human ITGB1 Protein, hFc Tag on SDS-PAGE under reducing condition.