| Cat.#: 11320 |
| Product Name: Human PDL2 Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: B7DC;bA574F11.2;Btdc;CD273;PD-L2;PDCD1L2;PDL2 |
| Target: PDL2 |
| UNIPROT ID: Q9BQ51 |
| Description: Recombinant human PDL2 protein with C-terminal 6xHis tag |
| Background: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).[UniProtKB/Swiss-Prot Function] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 23.4 kDa after removal of the signal peptide.The apparent molecular mass of PDL2-His is approximately 35-55 kDa due to glycosylation. |
| Molecular Characterization: PDL2(Leu20-Pro219) 6×His tag |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human PDL2 Protein, His Tag on SDS-PAGE under reducing condition. | 
Figure 2. Flow cytometry analysis with 15 µg/ml Human PDL2 Protein, His tag (11320) on Expi293 cells transfected with human PD1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
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