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Human PLAUR Protein, His Tag

Recombinant human PLAUR protein with C-terminal 6XHis tag
5/5

$659.00

Cat.#:  11578

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11578
Product Name:   Human PLAUR Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   U-PAR;uPAR;CD87
Target:    PLAUR
UNIPROT ID:    Q03405
Description:    Recombinant human PLAUR protein with C-terminal 6xHis tag
Background:     This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of PLAUR-His is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    PLAUR(Leu23-Arg303) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human PLAUR Protein, His Tag on SDS-PAGE under reducing condition.
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