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Human SIGLEC15 Protein, mFc-His Tag

Recombinant human SIGLEC15 protein with C-terminal mouse Fc and 6XHis tag


Cat.#:  11268

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11268
Product Name:   Human SIGLEC15 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD33 antigen-like 3;IGLEC-15;D33L3;ialic acid-binding Ig-like lectin 15;iglec15;iglec-15
Target:    SIGLEC15
Description:    Recombinant human SIGLEC15 protein with C-terminal mouse Fc and 6xHis tag
Background:     SIGLEC15 (Sialic Acid Binding Ig Like Lectin 15) is a Protein Coding gene. Diseases associated with SIGLEC15 include?Osteoporosis, Juvenile?and?Osteoporosis. Among its related pathways are?Innate Immune System?and?RET signaling. An important paralog of this gene is?SIGLEC1.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 53.6 kDa after removal of the signal peptide.The apparent molecular mass of SIGLEC15-mFc-His is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    SIGLEC15(Phe20-Thr263) mFc(Pro99-Lys330) 6×His tag
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human SIGLEC15 Protein, mFc-His Tag on SDS-PAGE under reducing condition.