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IDH1 mAb

Anti-IDH1 Mouse Monoclonal Antibody
5/5

$239.00

Cat.#:  26136

   Size:   100 μl

In Stock

          Product Description          
Anti-IDH1 Antibody
Cat. #:   26136
Gene Symbol:  IDH1
Description:   Anti-IDH1 Mouse Monoclonal Antibody
Background:   Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.
Immunogen:   Recombinant proteins of human IDH1 (amino acids 1-240).
Applications:   ELISA, WB, IHC, IP
Recommended Dilutions:    ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:100
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative:  No
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-IDH1 antibody recognizes IDH1 of vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing
Western blot:   Western blot analysis of recombinant IDH1 protein. Purified His-tagged IDH1 protein (amino acids 1-240) (Cat.#10198) was blotted with anti-IDH1 mouse antibody (Cat.# 26136).
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