Email: info@neweastbio.com   |  Call: 6109452007

Mouse DNAM-1 Protein, hFc Tag

Recombinant mouse DNAM-1 protein with C-terminal human Fc tag
5/5

$550.00

Cat.#:  12165

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     12165
Product Name:   Mouse DNAM-1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD226;PTA1
Target:    DNAM-1
UNIPROT ID:    Q5DW69
Description:    Recombinant mouse DNAM-1 protein with C-terminal human Fc tag
Background:     Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 52.9 kDa after removal of the signal peptide. The apparent molecular mass of mDNAM-1-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    Mouse DNAM-1(Glu19-Pro254) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse DNAM1 Protein, hFc Tag on SDS-PAGE under reducing condition.
          Publications