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Mouse IL17RA Protein, His Tag

Recombinant mouse IL17RA protein with C-terminal 6XHis tag
5/5

$659.00

Cat.#:  12176

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     12176
Product Name:   Mouse IL17RA Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   IL-17RA;CD217
Target:    IL17RA
UNIPROT ID:    Q60943
Description:    Recombinant mouse IL17RA protein with C-terminal 6xHis tag
Background:     Receptor for IL17A (PubMed:17911633, PubMed:20554964, PubMed:8777726). Receptor for IL17F (PubMed:17911633, PubMed:20554964). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (By similarity). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (By similarity). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848, PubMed:21993849, PubMed:21982598). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (By similarity).[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 34.1kDa after removal of the signal peptide. The apparent molecular mass of mIL17RA-His is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    Mouse IL17RA(Ser32-Trp322) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse IL17RA Protein, His Tag on SDS-PAGE under reducing condition.
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