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Human PVRIG Full Length Protein

Human PVRIG Full Length Protein-Synthetic Nanodisc


Cat.#:  11022

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11022
Product Name:   Human PVRIG Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   C7orf15; CD112R
Target:    PVRIG
Description:    Human PVRIG full length protein-synthetic nanodisc
Background:     Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Species/Host:    HEK293
Molecular Weight:    The human full length PVRIG protein has a MW of 34.3 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag PVRIG-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with PVRIG-Nanodisc is 12.91ng/ml.

Figure2. WB analysis of Human PVRIG-Nanodisc with anti-Flag monoclonal antibody at 1/5000 dilution, followed by Goat Anti-Rabbit IgG HRP at 1/5000 dilution