Subtotal:
$239.00
$659.00
| Cat.#: 11562 |
| Product Name: Human CD106 Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: VCAM1;V-CAM 1;VCAM-1;INCAM-100 |
| Target: CD106 |
| UNIPROT ID: P19320 |
| Description: Recombinant human CD106 protein with C-terminal 6xHis tag |
| Background: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 75.1 kDa after removal of the signal peptide. The apparent molecular mass of CD106-His is approximately 100-130 kDa due to glycosylation. |
| Molecular Characterization: CD106(Phe25-Glu698) 6×His tag |
| Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human CD106 Protein, His Tag on SDS-PAGE under reducing condition. |
